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I am new to content sites, and we're in the development/layout/design stage. I don't know anything about being a publisher at online ad networks, e.g., FastClick, DoubleClick, Adbility, and I'm trying to set aside space in the design for the most sought after ad sizes/places - for maximum profitability.
I don't know what the ad networks prefer and what types of spots pay the most. We're trying to prioritize just setting aside enough room for the best ad sizes so our visitors won't be annoyed with the advertising.
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