is there a difference between using adobe photoshop on a mac or pc?
as for me.. i prefer a PC in using photoshop, because i have used a pc my whole life, and i am familiar with all hotkeys and pc settings, but there are those who argue that im better off using a MAC for graphic design and should get one. i do know that macs are less virus and supposely better for graphic design, but isnt PC just fine also?

it really doesn't matter; it's all about what you're comfortable with. I grew up on macs since 1989 so i'm a bit biased

I've used both and the mac is way better than a pc. You can even run your pc inside a mac (using parallel) to illustrate goto the get a mac pages. http://www.apple.com/getamac/ads/

Never never will I ever use a pc running windows again (unless it's inside my mac)

there used to be a time when the differences were quite apparent, ie mac had a better gui and interface and PC had more computing power to offer to the designers. These days, the windows environment has matured quite a bit to compare fairly with Mac OS. Similarly Macs are also being shipped with intel processors so none can claim to have more computing power than the other. So it simply comes down what one is more comfortable with.

I think there was a time when a Mac was a much better machine for graphics, but I think the gap has pretty much closed. You should be fine using either a PC or a Mac.

You'll still see more graphic artists using a Mac than a PC in part because of where things used to be and in part because artists tend to be off the beaten path and will generally prefer something other than the norm.

The most important thing to remember is your computer Mac or PC is just a tool. You can create something great with even the worst tools. It's more how you make use of them than what they're capable of.

You can find people who could have every type of computer and every type of graphics software that wouldn't be able to come up with a decent image to save their life. And you'll find people who can create brillian designs on an old commodore 64 that they found in a attic an rebuilt.