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If anyone has CSS disabled in their browser, then all of my sites are stuffed. Very very few people would have CSS disabled these days. Search engine bots are the only major visitors who use text-only browsers.
As for Javascript, again the vast majority of people have this enabled. Obviously not nearly as much as CSS, but I'd still say somewhere about 90%+ probably. It might or might not be worth checking visitors browsers for this - it really depends on who your visitors are.
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