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Whether it works in Dreamweaver or not is beside the point.
A database has to "live" somewhere, and to integrate with a web site, it has to be accessible by the web server. So if your client is using GoDaddy or 1and1 or another hosting company, it's likely the web server is set up to run MySql and PHP. It's also possible you're hosting under Windows, in which case you'd have a SQL Server database an ASP/ASP.NET as a programming environment.
It's really a question of what the server will support. Community Server is an option under Windows, and there are a lot of wiki platforms you might be able to use under different platforms.
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